USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: Q9Y570 USC-OGP 2-DE database:  Q9Y570 Q9Y570 General information about the entry View entry in simple text format Entry name PPME1_HUMAN Primary accession number Q9Y570 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Protein phosphatase methylesterase 1; Short=PME-1; EC=3.1.1.89;. Gene name Name=PPME1 Synonyms=PME1 ORFNames=PP2593, PRO0750 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1173: pI=5.91; Mw=45157 SPOT OGP-1184: pI=5.92; Mw=43904 Cross-references UniProtKB/Swiss-Prot Q9Y570; PPME1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name PPME1_HUMAN Primary accession number Q9Y570 Secondary accession number(s) B3KMU6 B5MEE7 J3QT22 Q8WYG8 Q9NVT5 Q9UI18 Sequence was last modified on  January 23, 2007 (version 3) Annotations were last modified on  March 15, 2017 (version 148) Name and origin of the protein Description RecName: Full=Protein phosphatase methylesterase 1; Short=PME-1; EC=3.1.1.89; Gene name Name=PPME1 Synonyms=PME1 ORFNames=PP2593, PRO0750 Encoded on Name=PPME1; Synonyms=PME1; ORFNames=PP2593, PRO0750 Keywords 3D-structure; Alternative splicing; Complete proteome; Direct protein sequencing; Hydrolase; Methylation; Phosphoprotein; Reference proteome; Serine esterase. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF157028; AAD44976.1; -; mRNA EMBL AF111853; AAF16692.1; -; mRNA EMBL AK001381; BAA91661.1; -; mRNA EMBL AK022725; BAG51108.1; -; mRNA EMBL AK123288; BAC85574.1; -; mRNA EMBL AP000577; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AP002392; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471076; EAW74932.1; -; Genomic_DNA EMBL BC003046; AAH03046.1; -; mRNA EMBL BC050705; AAH50705.1; -; mRNA EMBL AF193049; AAG22477.1; ALT_SEQ; mRNA CCDS CCDS44678.1; -. [Q9Y570-1]; . CCDS CCDS60891.1; -. [Q9Y570-4]; . RefSeq NP_001258522.1; NM_001271593.1. [Q9Y570-4]; . RefSeq NP_057231.1; NM_016147.2. [Q9Y570-1]; . UniGene Hs.503251; -; . PDB 3C5V; X-ray; 2.00 A; A=39-386 PDB 3C5W; X-ray; 2.80 A; P=284-386 P=39-238 PDBsum; 3C5V; -; . PDBsum 3C5W; -; . ProteinModelPortal Q9Y570; -; . SMR Q9Y570; -; . BioGrid 119524; 97; . IntAct Q9Y570; 7; . STRING 9606.ENSP00000329867; -; . BindingDB Q9Y570; -; . ChEMBL CHEMBL1293320; -; . GuidetoPHARMACOLOGY 2875; -; . ESTHER human-PPME1; PPase_methylesterase_euk; . MEROPS S33.984; -; . iPTMnet Q9Y570; -; . PhosphoSitePlus Q9Y570; -; . SwissPalm Q9Y570; -; . DMDM 47606055; -; . REPRODUCTION-2DPAGE IPI00007694; -; . EPD Q9Y570; -; . PaxDb Q9Y570; -; . PeptideAtlas Q9Y570; -; . PRIDE Q9Y570; -; . DNASU 51400; -; . Ensembl ENST00000328257; ENSP00000329867; ENSG00000214517. [Q9Y570-1]; . Ensembl ENST00000398427; ENSP00000381461; ENSG00000214517. [Q9Y570-4]; . GeneID 51400; -; . KEGG hsa:51400; -; . UCSC uc001ouw.5; human. [Q9Y570-1]; . CTD 51400; -; . DisGeNET 51400; -; . GeneCards PPME1; -; . HGNC HGNC:30178; PPME1; . HPA CAB004541; -; . HPA HPA043900; -; . HPA HPA064396; -; . MIM 611117; gene; . neXtProt NX_Q9Y570; -; . OpenTargets ENSG00000214517; -; . PharmGKB PA142671152; -; . eggNOG KOG2564; Eukaryota; . eggNOG COG0596; LUCA; . GeneTree ENSGT00390000004396; -; . HOGENOM HOG000116699; -; . HOVERGEN HBG053622; -; . InParanoid Q9Y570; -; . KO K13617; -; . OMA RPWRWRT; -; . OrthoDB EOG091G0D0P; -; . PhylomeDB Q9Y570; -; . TreeFam TF314697; -; . BioCyc MetaCyc:MONOMER-16514; -; . BRENDA 3.1.1.89; 2681; . ChiTaRS PPME1; human; . EvolutionaryTrace Q9Y570; -; . GenomeRNAi 51400; -; . PRO PR:Q9Y570; -; . Proteomes UP000005640; Chromosome 11; . Bgee ENSG00000214517; -; . CleanEx HS_PPME1; -; . ExpressionAtlas Q9Y570; baseline and differential; . Genevisible Q9Y570; HS; . GO GO:0045296; F:cadherin binding; IDA:BHF-UCL; . GO GO:0051722; F:protein C-terminal methylesterase activity; IDA:HGNC; . GO GO:0051721; F:protein phosphatase 2A binding; IDA:HGNC; . GO GO:0019903; F:protein phosphatase binding; IDA:HGNC; . GO GO:0004864; F:protein phosphatase inhibitor activity; TAS:ProtInc; . GO GO:0019888; F:protein phosphatase regulator activity; TAS:HGNC; . GO GO:0006482; P:protein demethylation; IDA:HGNC; . Gene3D 3.40.50.1820; -; 2; . InterPro IPR029058; AB_hydrolase; . InterPro IPR000073; AB_hydrolase_1; . InterPro IPR016812; PPase_methylesterase_euk; . PANTHER PTHR14189; PTHR14189; 1; . Pfam PF12697; Abhydrolase_6; 1; . PIRSF PIRSF022950; PPase_methylesterase_euk; 1; . SUPFAM SSF53474; SSF53474; 2; . PROSITE PS00120; LIPASE_SER; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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